Rtw Investments, L.P. 13F annual report

Rtw Investments, L.P. is an investment fund managing more than $6.46 trillion ran by Roderick Wong. There are currently 67 companies in Mr. Wong’s portfolio. The largest investments include Madrigal Pharmaceuticals Inc and Rocket Pharmaceuticals Inc, together worth $918 billion.

Limited to 30 biggest holdings

$6.46 trillion Assets Under Management (AUM)

As of 7th August 2024, Rtw Investments, L.P.’s top holding is 1,915,862 shares of Madrigal Pharmaceuticals Inc currently worth over $537 billion and making up 8.3% of the portfolio value. Relative to the number of outstanding shares of Madrigal Pharmaceuticals Inc, Rtw Investments, L.P. owns less than approximately 0.1% of the company. In addition, the fund holds 17,687,772 shares of Rocket Pharmaceuticals Inc worth $381 billion, whose value fell 34.4% in the past six months. The third-largest holding is Axsome Therapeutics Inc worth $373 billion and the next is Avidity Biosciences worth $360 billion, with 8,806,838 shares owned.

Currently, Rtw Investments, L.P.'s portfolio is worth at least $6.46 trillion. The total portfolio value may be much higher due to cash assets that are not publicly disclosed such as fixed income, real estate, or cash equivalents.

Careers at Rtw Investments, L.P.

The Rtw Investments, L.P. office and employees reside in New York, New York. According to the last 13-F report filed with the SEC, Roderick Wong serves as the Managing Partner at Rtw Investments, L.P..

Recent trades

In the most recent 13F filing, Rtw Investments, L.P. revealed that it had opened a new position in Cullinan Therapeutics Inc and bought 1,052,630 shares worth $18.4 billion.

The investment fund also strengthened its position in Madrigal Pharmaceuticals Inc by buying 1,518,815 additional shares. This makes their stake in Madrigal Pharmaceuticals Inc total 1,915,862 shares worth $537 billion. Madrigal Pharmaceuticals Inc soared 39.6% in the past year.

On the other hand, there are companies that Rtw Investments, L.P. is getting rid of from its portfolio. Rtw Investments, L.P. closed its position in Avadel Pharmaceuticals plc on 14th August 2024. It sold the previously owned 8,798,558 shares for $149 billion. Roderick Wong also disclosed a decreased stake in Argenx Se by approximately 0.1%. This leaves the value of the investment at $281 billion and 654,430 shares.

One of the largest hedge funds

The two most similar investment funds to Rtw Investments, L.P. are Stephens Inc ar/ and Mondrian Investment Partners Ltd. They manage $6.43 trillion and $6.5 trillion respectively.


Roderick Wong investment strategy

Rtw Investments, L.P.’s portfolio is diversified across 2 sectors. Currently, their heaviest sector is Health Care — making up 80.6% of the total portfolio value. The fund focuses on investments in the United States as 52.2% of the portfolio companies are based in the United States.

The majority of the companies in the fund’s portfolio are small-cap stocks. Stocks with a size of more than $100 million in market cap make up 6% of the total holdings value. On the other hand, large-cap stocks make up only 1.5% of the portfolio. The average market cap of the portfolio companies is close to $4.45 billion.

The complete list of Rtw Investments, L.P. trades based on 13F SEC filings

These positions were updated on August 14th based on the fund’s latest 13F filing. Quickly find out what the most recently closed or increased positions are.

Security Shares Owned Value Allocation
Madrigal Pharmaceuticals Inc
382.53%
1,915,862
$536,747,898,000 8.31%
Rocket Pharmaceuticals Inc
No change
17,687,772
$380,817,731,000 5.90%
Axsome Therapeutics Inc
3.15%
4,634,331
$373,063,646,000 5.78%
Avidity Biosciences, Inc.
10.50%
8,806,838
$359,759,332,000 5.57%
Argenx Se
1.91%
654,430
$281,431,077,000 4.36%
Natera Inc
No change
2,593,323
$280,830,948,000 4.35%
Merus N.V
1.46%
4,169,393
$246,702,984,000 3.82%
Insmed Inc
95.17%
3,640,108
$243,887,236,000 3.78%
PTC Therapeutics Inc
0.42%
7,393,127
$226,081,824,000 3.50%
Dyne Therapeutics, Inc.
106.60%
6,387,138
$225,402,100,000 3.49%
Acadia Pharmaceuticals Inc
0.88%
13,707,506
$222,746,973,000 3.45%
Bruker Corp
2.99%
3,444,095
$219,767,702,000 3.40%
Masimo Corp
No change
1,462,400
$184,174,656,000 2.85%
Protagonist Therapeutics Inc
0.55%
5,286,404
$183,173,899,000 2.84%
Alkermes plc
16.56%
7,056,988
$170,073,411,000 2.63%
Immunocore Hldgs Plc
19.10%
4,869,798
$165,037,454,000 2.56%
Avadel Pharmaceuticals plc
Closed
8,798,558
$148,607,645,000
Cytokinetics Inc
7.77%
2,721,158
$147,432,340,000 2.28%
Ultragenyx Pharmaceutical In
54.00%
3,259,927
$133,983,000,000 2.07%
Penumbra Inc
9.80%
742,105
$133,556,637,000 2.07%
Akero Therapeutics Inc
No change
5,431,985
$127,434,368,000 1.97%
Establishment Labs Holdings Inc
No change
2,675,703
$121,583,944,000 1.88%
Immatics N.v
No change
10,000,000
$116,200,000,000 1.80%
Stryker Corp.
Closed
321,000
$114,876,270,000
Radnet Inc
9.14%
1,856,010
$109,356,109,000 1.69%
Apogee Therapeutics Inc
9.91%
2,712,096
$106,720,978,000 1.65%
Shockwave Med Inc
Closed
288,684
$94,004,171,000
Tarsus Pharmaceuticals, Inc.
4.28%
3,412,486
$92,751,369,000 1.44%
Intuitive Surgical Inc
104.50%
202,456
$90,062,552,000 1.39%
Arvinas Inc
10.01%
2,967,897
$79,005,418,000 1.22%
Spyre Therapeutics Inc
45.93%
3,258,360
$76,604,044,000 1.19%
Cargo Therapeutics Inc
9.17%
4,078,122
$66,962,763,000 1.04%
Thermo Fisher Scientific Inc.
Closed
110,500
$64,223,705,000
UroGen Pharma Ltd
9.21%
3,557,347
$59,692,283,000 0.92%
Sage Therapeutics Inc
No change
5,480,577
$59,519,066,000 0.92%
89bio Inc
No change
7,378,548
$59,102,169,000 0.92%
Stoke Therapeutics, Inc.
No change
4,224,838
$57,077,561,000 0.88%
Orchestra Biomed Hldgs Inc
No change
5,620,640
$45,808,216,000 0.71%
Glaukos Corporation
557.06%
386,291
$45,717,540,000 0.71%
Cg Oncology Inc
224.91%
1,344,074
$42,432,416,000 0.66%
Taysha Gene Therapies, Inc.
1.11%
18,800,299
$42,112,670,000 0.65%
Neurogene Inc
39.19%
1,070,565
$38,957,860,000 0.60%
Gh Research Plc
No change
3,327,129
$38,794,324,000 0.60%
Janux Therapeutics Inc
Closed
1,000,000
$37,650,000,000
Vericel Corp
50.11%
801,397
$36,768,094,000 0.57%
Fulcrum Therapeutics Inc
No change
5,845,956
$36,244,927,000 0.56%
Cullinan Therapeutics Inc
Opened
1,052,630
$18,357,867,000 0.28%
Dianthus Therapeutics Inc
No change
666,667
$17,253,342,000 0.27%
Roivant Sciences Ltd
No change
1,454,273
$15,371,666,000 0.24%
Lenz Therapeutics Inc
No change
863,389
$14,927,996,000 0.23%
Tempus Ai Inc
Opened
400,000
$14,000,000,000 0.22%
Kyverna Therapeutics Inc
No change
1,852,711
$13,895,333,000 0.22%
Essa Pharma Inc
No change
2,298,662
$12,090,962,000 0.19%
Replimune Group Inc
Opened
1,133,787
$10,204,083,000 0.16%
10x Genomics, Inc.
67.66%
502,856
$9,780,549,000 0.15%
Tourmaline Bio Inc
No change
741,656
$9,537,696,000 0.15%
Viridian Therapeutics Inc
No change
605,816
$7,881,666,000 0.12%
Perceptive Cap Solutions Cor
Opened
742,500
$7,469,550,000 0.12%
Exact Sciences Corp.
Closed
95,000
$6,560,700,000
ARCA biopharma Inc
Opened
1,400,000
$5,362,000,000 0.08%
Immunic, Inc.
No change
4,567,717
$5,070,166,000 0.08%
Larimar Therapeutics, Inc.
Closed
650,000
$4,933,500,000
Structure Therapeutics Inc
Opened
125,000
$4,908,750,000 0.08%
Acelyrin Inc
No change
978,310
$4,314,347,000 0.07%
Milestone Pharmaceuticals In
No change
3,256,102
$4,298,055,000 0.07%
Regenxbio Inc
No change
350,000
$4,095,000,000 0.06%
Allurion Technologies Inc
6.94%
3,697,549
$3,688,675,000 0.06%
Exagen Inc
0.48%
1,511,866
$2,751,596,000 0.04%
Sab Biotherapeutics Inc
16.44%
766,946
$2,377,533,000 0.04%
Beyond Air, Inc.
Closed
1,204,820
$2,096,387,000
Cutera Inc
No change
1,331,776
$2,010,982,000 0.03%
Sagimet Biosciences Inc
49.96%
500,000
$1,710,000,000 0.03%
Arya Sciences Acqu Corp Iv
No change
127,970
$1,467,816,000 0.02%
CytomX Therapeutics Inc
Opened
1,200,002
$1,464,002,000 0.02%
Adicet Bio Inc
74.52%
1,053,688
$1,274,962,000 0.02%
No transactions found
Showing first 500 out of 75 holdings